Grapes have been used for centuries to treat numerous conditions, according to the University of Maryland Medical Center. The leaves of the vine were used to treat inflammation and pain, and the unripened grapes were used to soothe sore throats. The grape seeds are even beneficial, as they are the source of grape seed extract, which offers several of its own medicinal benefits. It contains a number of natural compounds with potential health benefits. The most widely studied of these belong to a class called proanthocyanidins, compounds with strong antioxidant activity.

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